倍他司汀联合丁咯地尔治疗椎基底动脉供血不足疗效观察

Therapeutic Observation of hetahistine injection combined with bui]omedil injection in VBI treatment

目的 探讨倍他司汀与丁咯地尔治疗椎基底动脉供血不足的疗效和安全性.方法 将227例椎基底动脉供血不足患者随机分为治疗组118例和对照组109例;治疗组用倍他司汀与丁咯地尔静脉滴注;对照组用倍他司汀与天麻素注射液静脉滴注,观察两组治疗前后临床疗效、血流变学和血流动力学指标.结果 在改善患者的症状、血流变学和血流动力学指标上,治疗组疗效明显优于对照组,治疗组总有效率96.6%,对照组总有效率77.1%,两组在疗效上差异有显著性（P〈0.05）.结论 治疗组比对照组起效快、作用强、效果好、安全性可靠.

Objective To investigate the therapeutic effects and safety of buflomedil injection and buflomedil injection on the patients with VBI. Methods The VBI patients were divided into two groups randomly： the treatment group （ n=118） and the control group （ n= 109 ）. The patients in the treatment group got intravenous drips of binjeetion and buflomedil injection. The patients in the control group received intravenous drip of gastrodin injection. The changes in the clinical therapeutic were observed, such as hemorheology and hemodynamics of the groups be fore and after the treatment. Results Therapeutic outcome of the treatment group was obviously better than that. of the control group in improving patients symptom , hemorheology and hemodynamics with the cure rate 96.6% vs 77.1%, which was really significant （P〈0.05）. Conclususion The treatment group with betahistine injection combined with buflomedil injection has quicker, stronger and better effect and was reliably safe.