原发性肝癌超声检出率及临床分析

Clinical analysis and ultrasound detectable rate of primary hepatic carcinoma

目的探讨原发性肝癌检出率及危险因素。方法应用B超、彩色多普勒血流显像（CDFI）及三维彩色血管能量成像（3D－CPA）检查10，383例肝脏。结果正常组肝癌检出率为0．14％，脂肪肝组检出率为0．84％，慢性肝炎及HBV感染组检出率为10．56％，肝硬化组检出率为36．61％。与正常组比较，肝癌发生危险度在肝硬化组最高（RR＝261．5，95CI＝140．45～47914），依次为慢性肝炎、HBV感染组（RR＝75．43，95％CI＝40．21～137．53）及脂肪肝组（RR＝6．00，95％CI＝3．22～1836）。结论慢性肝炎、HBV感染、肝硬化中原发性肝癌发生危险度高；脂肪肝和慢性肝炎、HBV感染及肝硬化一样同属原发性肝癌的高危人群。

Objective To clarify the detectable rate of primary hepatic carcinoma(PHC)and risk factiors. Methods The liver screen in 10, 383 patients was conducted with ultrasound, color Doppler flow imaging (CDFI)and 3D color power angio (3D-CPA).Results The detectable rate of PHC was 0. 14 % in normal group, 0. 84 % in fatty livers, 10. 56% in the group with chronic hepatopathy or HBV infected patients, and 36. 61 % in the cirrhosis group. Compared with normal group, the relative risk of PHC in the cirrhosis group is the highest among all the groups(RR = 261. 5, 95 %Cl= 140. 45～479.14),the relative risks become lower, in group of chronic hepatopathy or HBV infected patients(RR = 75. 43,95 %CI = 40. 21 ～ 137. 53), and in fatty livers (RR = 6. 00, 95 %CI = 3. 22～ 18. 36 ) successively. Conclu-sion Relative risk of PHC in the patients with chronic hepatopathy,HBV infection and cirrhosis was high. Fatty liver is as a high risk factor of the PHC as chronic hepatopathy or HBV infection and cirrhosis.