胸腺肽联合猪苓多糖及乙肝疫苗治疗慢性乙型肝炎疗效观察

THE CURATIVE EFFECTS OF THYMOSIN COMBINED WITH ZHULING POLYSACCHARIDE AND HEPATITIS B V ACCINE IN CHRONIC HEPATITIS B

目的：本研究选择慢性乙型肝炎（ＣＨＢ）８０例；方法：分中等剂量胸腺肽联合猪苓多糖及乙肝疫苗组，猪苓多糖联合乙肝疫苗组和一般护肝治疗三组；结果：表明中等剂量胸腺肽联合猪苓多糖及乙肝疫苗可以促使ＡＬＴ复常，促使ＨＢｅＡｇ和ＨＢＶ—ＤＮＡ阴转；结论：其疗效优于猪苓多糖联合乙肝疫苗组，优于一般护肝组，且使用安全，可作为阻断或抑制ＨＢＶ复制的一种新方法。

Objective:The study was performed with chronic hepatitis B as to discuss clinic effect.Method:This study enrolled 80 patients diagnosed as chronic hepatitis B (CHB)according to the diagnostic criteria.They were divided into three groups,namely,the middle dose thymosin combined with ZHULING polysaccharide and hepatitis B V accine treatment group (30 patients );The ZHULING polysaccharied combined with heaptitis B V accine (20 patients);The ordinary liver protective group (30 patients).Result:After being treated,it was found that the middle dose could promote the recovery of ALT,promote the seroconversion of HBeAg and HBV DNA.Conclusion:Its cruative effects were much better than that of the ZHULING polysaccharide combined with hepatitis B V accine treatment group,the ordinary liver protective group,furthermore it was safe.As a result,it was believed that using middle dose for the treatment of HB might be a new therapeutic method.