中药抗痫胶囊对脑电图癫痫异常放电影响的临床与实验研究

Clinical and Experimental Studies on Anti epilepsy Capsule's Effect to Abnormal Electric discharge of Electroencephalograph

以脑电图为观察指标，从临床与实验两个角度研究抗痫胶囊对癫痫异常放电的影响。结果，临床用药４周，可明显缩短癫痫患儿脑电图癫痫异常放电的累计时间，与用药前比较，Ｐ＜０．０５，在脑电图改善的同时，临床发作次数也相应地减少或消失；即时实验用药，可使戊四氮诱发的大白鼠脑电图阵发性棘波样改变的持续时间明显缩短，与模型对照组比较，Ｐ＜０．００１。

The effects of anti epilepsy capsule to abnormal electric discharge of epilepsy were taken from both clinical and experimental studies,which EEG was an indicator.The results showed that this drug taken for four weeks could decrease the accumulated time of epilepsy like electric discharge in children with epilepsy,when it was compared with that before this drug taken,the P<0 05,and the seizure of epilepsy decrease or disappear correspondingly.This drug could shorten the lasting time of spike wave in rats induced by pentylenetetrazol,when it was compared with the group of epilepsy model,P<0 001.