胸部肿瘤合并重度缺血性心脏病的外科治疗

Research on surgical treatment for patients with chest tumor and severe ischemic heart disease

目的分析胸部肿瘤合并重度缺血性心脏病患者进行同期或分期外科手术治疗的效果。方法根据本研究的纳入和排除标准,选择2001年1月至2006年12月到济宁医学院附属第一人民医院就诊的57例胸部肿瘤合并重度缺血性心脏病病例,随机分为手术治疗组和非手术治疗组,手术治疗组进行同期或分期外科手术治疗胸部肿瘤及心脏病,非手术治疗组采取常规化疗、放疗、抗凝、扩冠及增加免疫力等治疗方法。比较两组患者1 a和3 a生存率的差异。结果手术治疗组21例,非手术治疗组36例,两组在年龄、性别、胸部肿瘤构成、病情严重程度等方面差别无统计学意义。手术治疗组和保守治疗组的1 a生存率分别为95.2%,91.7%(χ2=0.001,P=0.999),3 a生存率分别为76.2%、33.3%(2χ=9.747,P=0.000)。结论胸部肿瘤合并冠心病患者行手术治疗,3 a生存年限高于非手术组。

Objective To analyze effect of patients with chest tumor and severe ischemic heart disease carried on surgical operation treatments.Methods According to inclusion and exclusion criteria of this research,57 cases with chest tumor and severe ischemic heart disease from January 2001 to December 2006 were selected and randomly divided into treatment group and non-surgical treatment group,The treatment group were performed the same period or stage surgery,treatments of conventional chemotherapy,radiation therapy,anticoagulation,expansion of coronary artery and increasing the immune system were adopted in non-surgical treatment group.To compare the differences in 1 year and 3 year survival rate.Results There are 21 cases of surgery group,36 cases of non-surgical treatment,and no significant difference from two groups in age,sex,chest tumor composition and the severity.The 1-year survival rate in two groups were 95.2% and 91.7%（χ2=0.001,P=0.999）,3-year survival rate were 76.2% and 33.3%（χ2=0.001,P=0.999）.Conclusion There is a obvious difference between two groups in 3-year survival rate,The effect of surgical treatment for patients with chest tumor is better than that the non-surgical treatment group.