摘要
目的:分析金玄痔科熏洗散方中植物药超临界CO_2萃取物的化学成分组成,诠释该中药复方制剂的药效物质基础。方法:采用超临界CO_2萃取法得到超临界CO_2萃取物,通过气相色谱-质谱法对其成分进行了分析鉴定。结果:共分离出34种成分,鉴定了其中33种化合物;主要成分为胡薄荷酮(23.17%),棕榈酸(17.31%)、顺-5-甲基-2-(1-甲基乙基)环己酮(11.74%)。结论:分析鉴定了金玄痔科熏洗散方中植物药超临界CO_2萃取物有效物质部位中的33种化合物,占其总量的99%以上,这对于诠释该中药复方制剂的药效物质基础具有重要意义。
Objective： To analysis the chemical components of supercritical CO2 extraction in jinxuan zhike xunxi powders prescription of herbal medicine and explain the medicine material basis of traditional chinese medicine compounds. Method： The supercritical CO2 extraction was got by supercritical CO2 extract, the chemical components was identified by GC-MS. Result： Thirty-four components were separated and 33 components were identified. The main components were pulegone （23. 17%）, palmitic ＇acid （ 17.31% ）, cis-5 -methyl-2- （ 1 -methylethyl） Cyclohexanone （ 11.74% ）. Conclusion： The 33 components are separated and identified, accounting for 99. 58% in the total, which is provided with important significance for explaining the medicine material basis of traditional chinese medicine compounds.
出处
《中国药师》
CAS
2010年第12期1710-1712,共3页
China Pharmacist
