期刊文献+

辛伐他汀治疗老年人急性脑梗死的临床疗效观察 被引量:1

Clinical observation of Simvastatin in the treatment of acute cerebral infarction of the elderly
下载PDF
导出
摘要 目的探讨辛伐他汀治疗老年人急性脑梗死的疗效。方法对我科2006年7月至2010年06月收治的老年人急性脑梗死60例进行分组治疗。其中治疗组30例常规治疗同时合并辛伐他汀10mg、1次/d、晚睡前口服14d,另外对照组30例采用常规治疗。结果治疗组NDS评分及NIHSS评分和临床疗效及血脂变化优于对照组,两组比较差异有统计学意义(P<0.05)。结论辛伐他汀治疗老年人急性脑梗死具有良好的疗效。 Objective To investigate Simvastatin in the treatment of acute cerebral infarction of the elderly. Methods Carried on the grouping treatment of 60 cases of acute cerebral infarction from July 2006 to June 2010. Including 30 cases were treated with conventional treatment and 10 mg simvastatin,one,night bedtime oral,14 days. In the control group 30 cases with conventional treatment. Results The NDS score and NIHSS score and clinical efficacy and Lipid changes,the treatment group was better than the control group,difference between the two groups was statistically significant ( P〈0. 05). Conclusion Simvastatin in the elderly of acute cerebral infarction has a good effect.
作者 魏敏 李然
出处 《中国实用医药》 2010年第34期9-10,共2页 China Practical Medicine
关键词 辛伐他汀 老年人 急性脑梗死 Simvastatin the elderly acute cerebral infarction
  • 相关文献

参考文献3

  • 1"关注脑动脉粥样硬化"神经科专家会.他汀抗动脉粥样硬化揭开卒中防治新篇章.中国医学论坛报,循环周刊,2009-04-02:C15.
  • 2赵水平.血脂与动脉粥样硬化及其干预新动向[J].中国动脉硬化杂志,2009,17(3):169-171. 被引量:43
  • 3Leepee NJ,Ardchali R,deGoma EM,et al.Statin use in patients with extremely low low Density lipoprotein levels is associated with improvedsurvival.Circulation,2007,116(6):613-618.

二级参考文献13

  • 1Tabas I, Williams K J, Boren J. Subendothelial lipoprotein retention as the initiating process in atherosclerasis: update and therapeutic implications [ J ]. Circulcaion, 2007, 116 ( 16 ) :1 832-844.
  • 2Steinberg D, Glass CK, Witztum JL. Evidence mandating earlier and more aggressive treatment of hypercholesterolemia [ J ]. Circulation, 2008, 118 (6) : 672-677.
  • 3Rodenburg J, Vissers MN, Wiegman A, et al. Statin treatment in children with familial hypercbelesterolemia: the younger, the better [ J ]. Circtdation, 2007, 116 (6) : 664 - 668.
  • 4Schunkert H, Samani NJU. Elevated C-reactive protein in atherosclerosischicken or egg [J]? N Engl J Med, 2008, 359 (1): 1 953-955.
  • 5Grundy SM, Gleeman Jl, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel Ⅲ guidelines[J]. Circulation, 2004, 110 (2) : 227 - 239.
  • 6Robinson JG. Models for describing relations among the various statin drugs, low-desity lipoprotein cholesterol lowering, pleiotropic effects, and cardiovascular risk [J]. Am J Cardiol, 2008, 101 (7) : 1 009-015.
  • 7Leeper N J, Ardehali R, deGoma EM, et al. Statin use in patients with extremely low low-density lipoprotein levels is associated with improved survival [J]. Circulation, 2007, 116 (6) : 613-618.
  • 8Brunzell JD, Davidson M, Furberg CD. Lipoprotein management in patients with cardiometabolic risk. Consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation [J]. JACC, 2008, 51 (15): 1 512-524.
  • 9Kastelein JJP, Akdim F, Stroes ESG. Simvastatin with or without ezetimibe in familial hypereholesterolemia [ J ]. N Engl J Med, 2008, 358 (14): 1 431-443.
  • 10Rosseb AB, Pedersen TR, Boman K. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis [ J ]. N Engl J Med, 2008, 359 (13) : 1 343-356.

共引文献42

同被引文献7

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部