摘要
目的探讨乙型肝炎病毒与前S1抗原的相关性。方法采用ELISA检测296例乙型肝炎病毒感染者血清中的前S1抗原。结果在55例HBeAg阳性标本中前S1抗原阳性的47例,阳性率85.4%;178例HBeAg阴性而抗HBeAb阳性的标本中前S1抗原阳性的115例,阳性率64.6.0%;63例HBeAg和抗HBe均阴性的血清中前S1抗原阳性仅39例,阳性率61.9%;前S1抗原在血清学表达上与HBeAg的阳性符合率高达85.4%。结论乙型肝炎病毒前S1抗原与HBeAg阳性高度相关,血清前S1抗原是乙肝病毒在体内复制的可靠标志。
Objective To discussthe recationshipbetweenPreS1 andhepatitisB virus. Methods The adoption ELISA determines the PreS1 296 cases of the patients of hepatitis B virus in fected in serum. Results 47 cases of PreS1 antigen positive were found in 55 cases,its preS1 positive rate was 84. 4% ,115 cases of 178 were positive. Its PreS1 positive rate was64. 6% ,only 39 cases were found in serum of the patiens that HBeAg and Antr HBe both were negative,The prescontigen match the rate with HBeAg on the serum learn to express high amount to 85. 4%. Conclusion PreSl Ag of HBV is highly recated to HBeAg. PreS1 is the recicabce marker of hepatitis B virus.
出处
《中国实用医药》
2010年第34期47-48,共2页
China Practical Medicine
