心理干预联合高压氧治疗对脑卒中后抑郁患者生命质量的影响

Effect of psychological intervention combined with hyperbaric oxygen therapy on the quality of life of patients with depression after cerebral stroke

目的探讨心理干预联合高压氧治疗对脑卒中后抑郁患者生命质量的影响。方法对符合脑卒中后抑郁诊断标准的45例患者随机分为两组，对照组（n=23）给予改善脑循环、抗抑郁、营养神经药物应用及相应护理等常规治疗；试验组（n=22）在常规治疗的基础上给予心理干预联合高压氧治疗；8周为1疗程。于入组时和8周末采用汉密顿抑郁量表（HAMD）对两组患者各调查评定1次，并在8周末应用生活质量指数问卷（QL-INDEX）对两组患者进行评定。结果人组时两组患者HAMD评分差异无统计学意义（P〉0．05），8周末试验组与对照组HAMD评分比较显著降低（P〈0．01）；8周末生活质量总指数试验组为（8．57±1．94），对照组为（7．30±1．98），差异有统计学意义（P〈0．05）。结论心理干预联合高压氧治疗有助于改善脑卒中后抑郁患者的心理状态，增加治疗效果，提高患者的生命质量。

Objective To investigate the effect of the psychological intervention combined with hyper- baric oxygen therapy on the mental status and the quality of life of patients with depression after cerebral stroke. Methods 45 patients with depression after cerebral stroke were randomly divided into the study group （ n = 22） and the control group （ n = 23 ）. The two groups had the same clinical routine treatments including improving cerebral cirulation, reducing intracranial pressure, drugs to anti-infection, nervous nutrition and corresponding op- eration for 8 weeks as a course of treatment, and psychological behavior intervention combined with hyperbaric oxygen therapy was added to the study group. The scores of Hamilton depression rating scale （HAMD） on both groups were evaluated before and spitzer＇ s quality of life index（QL-INDEX） were used and investigated on two groups at the end of 8 weeks. Results There was no significant difference on the scores of HAMD between the two groups before therapy （ P 〉 0. 05 ）. The scores on HAMD of the study group after the treatment notably dropped compared to the control group（ P 〈 0. 01 ）. The difference of the scores on ,group index of quality of life between the study group （ 8.57 ± 1.94 ） and the control group （ 7. 30 ± 1.98 ） had statistical significance （ P 〈 0.05）. Conclusion Psychological intervention combined with hyperbaric oxygen therapy plays an important role in the treatment of patient with depression after cerebral stroke to improve their mental status, treatment ef- fectiveness and quality of life.