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左乙拉西坦添加治疗肌阵挛-失张力癫癇4例报道 被引量:5

Levetiracetam as an Add-on Therapy in Children with Myoclonic-astatic Epilepsy: 4 Cases Report
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摘要 目的:探讨左乙拉西坦添加治疗肌阵挛-失张力癫癇(MAE)的有效性及安全性。方法:回顾分析4例左乙拉西坦添加治疗的MAE病例,并结合国外相关文献分析其有效性和安全性。结果:4例MAE患者添加左乙拉西坦治疗后癫癇发作均明显减少,其中3例完全无发作,最长无发作时间达6个月,并且无明显不良反应。结论:左乙拉西坦添加治疗MAE可能是一较好的治疗方案。 To discuss the efficiency and safety of levetiracetam as an add-on therapy on myoclonic- astatic epilepsy. Methods: 4 cases who used levetiracetam as an add-on therapy were reviewed and analyzed, combining with the related overseas and domestic research materials. Results: After adding levetiracetam, seizures in all cases were reduced obviously without apparent side-effect. 3 of them were seizure-free and the longest time without any epileptic event was up to 6 months. Conclusion: Levetiracetam may be effective and considered as an add-on treatment in children with MAE.
出处 《中国临床神经科学》 2010年第6期606-609,共4页 Chinese Journal of Clinical Neurosciences
基金 国家自然科学基金资助项目(编号:30700247)
关键词 左乙拉西坦 癫癇 肌阵挛-失张力 levetiracetam epilepsy myoclonic-astatic
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参考文献8

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同被引文献109

  • 1田国红,赵忠新.左乙拉西坦——一种具有全新作用机制的抗癫痫新药[J].中国新药与临床杂志,2006,25(10):782-786. 被引量:43
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  • 9Michaelides C,Thibert RL,Shapiro MJ,et al.Tolerability and dosing experience of intravenous levetiracetam in children and infants[J].Epilepsy Res,2008,81:143-147.
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