益肾培督法治疗肾虚督寒型强直性脊柱炎疗效评价

Curative Effect Assessment of Yishenpeidu Method on Ankylosing Spondylitis of Syndrome of Kidney Deficiency and Du Meridian Cold

目的:观察益肾培督法治疗肾虚督寒型强直性脊柱炎的临床疗效。方法:将68例患者随机分为治疗组和对照组,治疗组采用益肾培督的中药协定方,对照组采用缓解病情的西药。疗程为3个月。治疗前后评价强脊疾病活动指数(BASDAI)、疾病功能指数(BASFI)、晨僵时间、胸廓活动度、指地距、枕墙距、Schober试验、血沉(ESR)、C-反应蛋白(CRP)、血尿常规、肝肾功能、大便隐血。结果:治疗后两组除枕墙距以外其余指标和治疗前相比差异均有统计学意义(P<0.05或P<0.01);两组患者综合疗效比较差异无统计学意义(P>0.05);两组间对比,治疗组的晨僵时间改善及不良反应发生情况明显优于对照组(P<0.05)。结论:益肾培督法对强直性脊柱炎有较好的疗效,且安全可靠。

Objective：To observe the clinical effect of Yishenpeidu method on ankylosing spondylitis of syndrome of kidney deficiency and Du meridian cold.Methods：68 cases were randomly divided into treatment group and control group, Yishenpeidu Formula were taken in the treatment group and the western medicine relieving the symptom of AS were taken in the control group, 3 mouths for a course. The following indicators were used to detect before and after treatment： BASDAI score, BASFI score, time of morning stiffness, thoracic expansion degrees, refers to land distance, pillow-wall distance, Schober test, ESR,C-reactive protein, the regular test of blood and urine, the test of liver and kidney function, blood of feces.Results：The both groups after treatment compared with pre-treatment significantly improved in other indicators except for pillow-wall distance and the difference is statistically significant（P〉0.05 or P〉0.01）; The total effect of both the treatment group and the control group is not statistically significant（P〉0.05）; Improvement in time of morning stiffness and adverse effects of the treatment group are better than those of the control group（P〉0.05）.Conclusion：Yishenpeidu method can increase the efficacy of therapy for AS , safe and reliable.