消渴丸治疗2型糖尿病的药物经济学评价

Economic Evaluation of Xiaoke Wan on Treating Type 2 Diabetes Mellitus

目的分析服用消渴丸控制血糖的成本-效果比。方法调查纳入合格样本,对病例按用药情况分为消渴丸组(69例)与非消渴丸组(89例),观察周期为两个月。采用《消渴丸及其他降糖药临床应用登记表》,记录病人性别、年龄、生活习惯、体征及身体状况等基本情况,采用《用药情况记录》,记录病人观察期间用药情况和分段收集病人测量血糖情况,采用卡方分析消渴丸服药前后血糖控制情况。服用2个月后复查空腹血糖(FPG)、餐后2小时血糖(2hPG)。以《中药新药治疗消渴病的临床研究指导原则》制定的标准判断疗效。结果消渴丸组与非消渴丸组相比,显效无明显差异(P>0.05),但消渴丸组成本-效果比较低。也就是说,消渴丸组较非消渴丸组获得相同效果的同时,所需费用较低。在校正了药品价格下降的因素后,消渴丸组成本-效果比仍为较低。结论服用消渴丸可能较单纯西药更有优势。

Objective To analyze cost-effect ratio of taking Xiaoke wan to control blood glucose. Methods The survey cases were divided into Xiaoke wan group（69 cases） and non-diabetes pill group（89 cases） ,with two months of observation period. Two months later fasting plasma glucose（FPG） ,2-hour postprandial blood glucose（2 h PG） was reviewed,and the clinical effects were observed. Results In contrast to non-diabetes pill group,Xiaoke wan group had no significant difference（P 0.05） in significant effect,but was relatively low in cost-effect. In other words,Xiaoke wan group cost lower than non-diabetes pill group in obtaining the same effects. Conclusion Taking Xiaoke wan may be more advantagous than simply Western drugs.