摘要
目的本文通过研究Ca(OH)2―H3PO4体系合成HA的反应机理,优化了HA合成工艺;方法采用PHS-25数显pH计对不同H3PO4滴定速率下的反应液的pH值进行监测,并应用X射线衍射(XRD)对不同滴速下合成样品进行物相分析;结果研究表明,当磷酸滴定1小时时,Ca2+与PO43-达到动态反应平衡,合成产物为单一相的HA;结论根据Ca(OH)2—H3PO4液固反应模型,合成HA的关键是保证Ca(OH)2―H3PO4液固反应体系的溶解、电离平衡。
Objective Based on studying the reaction mechanism of HA synthesis with Ca（OH）2―H3PO4 reaction system,the synthesis process of HA was optimized.Methods The pH value of reaction solution with different dropping rate of H3PO4 was monitored by the Digital pH Meter,And the phsse composition of HA powders synthesized with different dropping rate of H3PO4 were chractered by means of X-ray diffraction（XRD）.Results It was studied that Ca2＋ and PO43- reached the balance of dynamic reaction when phosphoric acid was titrated for an hour and the pure HA was obtained.Conclusion The key of HA synthesis was the balance of dissolving and ionizing with Ca（OH）2―H3PO4 reaction system.
出处
《生物骨科材料与临床研究》
CAS
2010年第6期15-17,20,共4页
Orthopaedic Biomechanics Materials and Clinical Study
关键词
羟基磷灰石
反应机理
液固反应模型
Hydroxyapatite
Reaction MecHAnism
The Liquid-solid reaction model
