血液病患者医院感染的临床分析

Nosocomial Infection in Patients with Hematologic Diseases:A Clinical Analysis

目的研究血液病患者医院感染的特点,为制定医院感染控制措施提供理论依据。方法采用回顾性分析方法,对2007年1月-2008年6月1339例血液病患者进行医院感染的相关临床分析。结果 1339例血液病患者中发生医院感染434例,医院感染发病率为32.4%;感染部位主要以呼吸道为主占58.1%,其次是口腔、血液、消化道等;病原菌以革兰阴性菌为主占55.9%;患者原发病类型为急性白血病、合并糖尿病及住院时间长是血液病患者医院感染发生的危险因素。结论血液病患者易并发医院感染,应根据其疾病特点加强监护,针对危险因素进行监测,使医院感染得到有效控制。

OBJECTIVE To investigate the characteristics of nosocomial infection in patients with hematologic diseases,and provide the theoretic bases for making the controlling measures of nosocomial infection.METHODS Totally 1339 patients with hematologic diseases in our hospital between Jan 2007 and Jun 2008 were analyzed retrospectively.RESULTS Among them the incidence of nosocomial infection was 32.4%（434/1339）.The main infection site was respiratory tract,and then the oral cavity,blood,gastrointestinal tract and so on.Gram-negative bacteria were the most common pathogens.Acute leukemia,complicating diabetes mellitus and long hospitalization duration were the risk factors of nosocomial infection in patients with hematologic diseases.CONCLUSION Patients with hematologic diseases are susceptible to nosocomial infection,they should be cared intensively according to their characteristics and monitored to aim directly at risk factors of nosocomial infection so as to control nosocomial infections effectively.