手术后医院感染常见病原菌与耐药性分析

Drug Resistance of Common Pathogens Causing Nosocomial Infection after Operation

目的了解综合性医院外科手术后患者感染病原菌及其耐药性。方法对2009年1-12月外科手术后感染送检标本,进行培养分离致病菌,采用WalkAway240全自动细菌鉴定及药敏测试仪进行了分析。结果培养出的病原菌中革兰阴性杆菌占74.0%,革兰阳性球菌占26.0%,常见病原菌主要为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌,其对万古霉素和亚胺培南具有较好抗菌效果。结论加强感染菌和耐药性的监测,采用合理预防控制措施,延缓细菌耐药。

OBJECTIVE To know about the detection and drug resistance of pathogens of infected patients after operation in a general hospital.METHODS Pathogens were cultured and isolated from the specimens of infected patients post operation from Jan to Dec 2009.WalkAway240 Phoenix system,instrument for drug sensitivity test and NC31 certified plate were used to analyze the pathogens.RESULTS Among the cultured pathogens,Gram-negative bacilli were 74.0%,and Gram-positive cocci were 26.0%.The common pathogens were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,and Staphylococcus aureus.Vancomycin and imipenem had good antibacterial effect to the above bacteria.CONCLUSION Target monitoring to the drug resistance of pathogens should be strengthened,the reasonable measures should be taken to decrease the occurrence of drug resistance of pathogens.