期刊文献+

布托啡诺在麻醉后监护病房使用的临床观察

下载PDF
导出
摘要 目的观察布托啡诺在全麻手术后进入麻醉后监护病房(PACU)的患者的应用效果和不良反应。方法选择60例腹部手术全麻患者术后按随机数字表法分为2组:布托啡诺组(A组=30例)、芬太尼组(B组=30例),A组给予酒石酸布托啡诺1 mg静脉注射;B组给予芬太尼0.05 mg静脉注射。观察并记录A、B 2组注药后5、10、15、30、45、60 min疼痛评分、镇静评分、平均动脉压(MAP)、心率(HR)和呼吸抑制的发生情况,以及基础平均动脉压和心率并进行对照分析。结果 2组患者疼痛评分相当(P>0.05),A组镇静评分高于B组(P<0.05),2组对血压影响小,布托啡诺组可使心率下降至用药后30 min,但仍然在临床允许范围内,A组呼吸抑制低于B组(0%vs20%,P<0.05)。结论在PACU中使用常规临床剂量的布托啡诺能很好缓解疼痛,不良反应少。
作者 刘志毅
出处 《南昌大学学报(医学版)》 CAS 2010年第9期78-79,81,共3页 Journal of Nanchang University:Medical Sciences
  • 相关文献

参考文献1

二级参考文献13

  • 1Gillis JC, Benfield P, Goa KL. Transnasal butorphanol. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute pain management. Drugs 1995; 50:157-175.
  • 2Vandam LD. Drug therapy: butorphanol. N Engl J Med 1980; 302:381-384.
  • 3Scott JL, Smith MS, Sanford SM, Shesser RF, Rosenthal RE, Smith JP, Feied CF, Ghezzi KT, Hunt DM. Effectiveness of transnasal butorphanol for the treatment of musculoskeletal pain. Am J Emerg Med 1994; 12:469471.
  • 4Dale o, Hjortkjaer R, Kharasch ED. Nasal administration of opioids for pain management in adults. Acta Anaesthesiol Scand 2002; 46:759-770.
  • 5Hoffert MJ, Couch JR, Diamond S, Elkind AH, Goldstein J, Kohlerman NJ 3rd, Saper JR, Solomon S. Transnasal butorphanol in the treatment of acute migraine. Headache 1995; 35:65-69.
  • 6Rapoport AM, Bigal ME, Tepper SJ, Sheftell FD. Intranasal medications for the treatment of migraine and cluster headache. CNS Drugs 2004; 18:671-685.
  • 7Ladov MJ, Precheur HV, Rauch DM, Engel PS, Stern RK. An open-label evaluation of the efficacy and safety of Stadol NS with ibuprofen in the treatment of pain after removal of impacted wisdom teeth. J Oral Maxillofac Surg 2000; 58: 15-18.
  • 8Wermeling DP, Grant GM, Lee A, Alexander N, Rudy AC. Analgesic effects of intranasal butorphanol tartrate administered via a unit-dose device in the dental impaction pain model: a randomized, double-blind, placebo- controlled, parallel-group study. Clin Ther 2005; 27:430-440.
  • 9Olsen JC, McGrath NA, Schwarz DG, Cutcliffe BJ, Stern JL. A double-blind randomized clinical trial evaluating the analgesic efficacy of ketorolac versus butorphanol for patients with suspected biliary colic in the emergency department. Acad Emerg Med 2008; 15:718-722.
  • 10Abboud TK, Zhu J, Gangolly 1, Longhitano M, Swart F, Makar A, Chu G, Cool M, Mantilla M, Kurtz N. Transnasal butorphanol: a new method for pain relief in post-cesarean section pain. Acta Anaesthesiol Scand 1991; 35:14-18.

共引文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部