摘要
目的:了解南京地区病原菌感染的临床分布及其耐药性变化情况。方法:对2009年全年住院病人病原菌感染病例进行统计,并且对相应抗生素的耐药情况进行分析。结果:2009年度共分离临床菌株3346株,其中G-杆菌占56.3%,G+球菌占25%,真菌感染占18.7%。以铜绿假单胞菌、鲍曼不动杆菌、大肠埃希菌为代表的革兰阴性菌为最常见的临床分离细菌,耐药现象较为严重。大多数医院感染革兰阴性菌对加酶抑制剂抗菌药耐药率菌有不同程度的下降。结论:为减少病原菌感染的发生率及控制细菌耐药性必须加强抗生素的合理应用。
Objective：To explore the change of Clinical distribution and drug resistance analysis of hospital pathogens infections in Nanjing area.Methods：The patients infected with the pathogen were counted and the corresponding antibiotic resistance were analyzed during the year of 2009.Results：In the year of 2009,3346 clinical bacteriuma were isolated,and Gbacilus,G＋-coccus,fungi occupied 56.3%,25% and 18.7% respectively.The most common clinical isolated strains,such as gram-negative pseudomonas aerugi-nosa,acinetobacter baumannii,escherichia coli,have serious drug resistance.In most hospitals,the resistant rate of gram negative bacteriathe to antimicrobial drugs with enzyme inhibitors decreased differently.Conclusion：Rational application of antibiotic can be used to reduce the incidence of infection with pathogenic bacteria and the drug-resistance of bacteria.
出处
《现代生物医学进展》
CAS
2010年第22期4267-4270,共4页
Progress in Modern Biomedicine
关键词
病原菌
抗生素
耐药性
pathogenic bacteria
antibiotic
drug resistance
