同样的抗凝,为何不同的开通?——门静脉血栓程度的临床意义

Why is the recanalization rate different after the identical anticoagulation?——Clinical implications of degree of portal vein thrombosis

《肝脏病学》(Hepatology)杂志2010年1月刊登了一项有关急性门静脉血栓形成的抗凝治疗的前瞻性队列研究。这项研究较此前所有关于抗凝治疗门静脉血栓的研究更为重要。研究显示,在应用抗凝治疗后,门静脉比肠系膜上静脉和脾静脉的开通率更高。这一看似矛盾的现象引起了我们的关注,并对此作了进一步的分析。

A prospective multi-center cohort study entitled ＂＇Acute portal vein thrombosis unrelated to cirrhosis＂ was published in ＂Hepatology＂ on January, 2010. We read with very great interest the study from the European Network for Vascular Disorders of the Liver （EN-Vie） providing stronger evidence of anticoagulation for acute portal vein thrombosis （PVT） without cirrhosis than any previous retrospective studies with a smaller sample size. Despi＇te the clear and valuable results in the s＇~ud3＇, the ex~,stence of a stati.~ticalty significant difference between recanalization rate of portal vein and that of splenic or superior mesenteric vein is confusing. Thus we wrote a correspondence to the journal, focusing on the further analysis of the paradoxical problem.