摘要
借助于单细胞阳离子测定系统研究了α－石英诱发细胞毒性过程中，不同外钙浓度时粉防己碱作用后，细胞存活率与胞浆游离钙浓度的变化关系。研究发现粉防己碱可以通过阻断细胞离子通道，拮抗α－石英的细胞毒性。
\; By use
of the ARCMMIC system, the relationship between cells survival rate of alveolar macrophages
and the change of plasmic free Ca\+\{2+\} concentration ( \-i) after the action of quartz and
tetrandrine was investigated under different extracellular Ca\+\{2+\} concentration. The results
showed that tetrandrine could antagonize the cytotoxicity of quartz by blocking the calcium
channels of alveolar macrophages.\=\;
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
1999年第3期310-314,共5页
Chinese Journal of Inorganic Chemistry
基金
国家自然科学基金
关键词
粉防己碱
石英
细胞毒性
硅肺
钙离子
拮抗作用
tetrandrine\ \ \ quartz\ \ \ cytotoxicity\ \ \
silicosis\ \ \ calcium ion
