期刊文献+

4-(4-氨基苯氧基)-2-(烷基氨甲酰基)吡啶的合成

Synthesis of 4-(4-aminophenoxy)-2-(alkyl carbamoyl) pyridine
下载PDF
导出
摘要 Three kinds of 4-(4-aminophenoxy)-2-(alkyl carbamoyl)pyridines were synthesized respectively from three kinds of N-alkyl-4-chloro-2-pyridine carboxamides and p-aminophenol potassium,which were obtained from p-aminophenol and tert-butyl alcohol potassium with nitrogen protection in anhydrous DMF.The structures of the target compounds were characterized by IR,1HNMR and ESI-MS. Three kinds of 4-(4-aminophenoxy)-2-(alkyl carbamoyl)pyridines were synthesized respectively from three kinds of N-alkyl-4-chloro-2-pyridine carboxamides and p-aminophenol potassium,which were obtained from p-aminophenol and tert-butyl alcohol potassium with nitrogen protection in anhydrous DMF.The structures of the target compounds were characterized by IR,1HNMR and ESI-MS.
出处 《化学研究与应用》 CAS CSCD 北大核心 2010年第12期1601-1604,共4页 Chemical Research and Application
基金 河南省基础与前沿技术研究项目(082300420120)
关键词 4-氯-2-吡啶甲酸甲酯 对氨基苯酚钾 4-(4-氨基苯氧基)-2-(烷基胺甲酰基)吡啶 合成 4-chloropyridine-2-carboxylic acid methyl ester p-aminophenol potassium 4-(4-aminophenoxy)-2-(alkyl carbamoyl)pyridine synthesis
  • 相关文献

参考文献10

  • 1Loegers M,Gehring R,Kuhn O,et a1.Process for the preparalion of 4-4-[[4-chloro-3-(trifluoromethy1)pheny1] amino}carbony1)amino] phenoxy}-N-methyl-pyridine-2-carboxamide[P].WO:2006034796,2006-04-06.
  • 2杨吉春,刁杰,葛童,刘长令.吡啶类农药最新研究进展[J].农药,2007,46(1):1-9. 被引量:33
  • 3Kevin R.C,Cheng-yi Chen.Enantioselective Pd-catalyzed α-arylation of N-boc-pyrrolidi-ne:the key to an efficient and practical synthesis of a glucokinase activator[J].J.Org.Chem.,2006,128(11):3538-3539.
  • 4Finsinger D,Buchstaller H.P,Burgdorf L,et al.Preparation and formulations of diacylhydrazine derivatives capable of inhibiting raf-kinases[P].WO:2005058832A,2005-06-30.
  • 5Michael Kreis,Leverkusen,Edith Beckmann,et al.Heteroaryl aryl ethers[P].US:20100174089A1,2010-07-08.
  • 6赵乘有,陈林捷,许煦,罗晓燕,冀亚飞.对甲苯磺酸索拉非尼的合成[J].中国医药工业杂志,2007,38(9):614-616. 被引量:15
  • 7Van Acker,Koenraad Lodewijk August,Wigerinck Piet Tom Bert Paul,et al.Preparation of aminophenol derivatives as entry inhibitiors of the HIV virus[P].WO:2005023242A1,2005-3-17.
  • 8Borzilleri Robert M,Cornelius Lyndon A.M,Schmidt Robert J,et al.Preparation of monocyclic heterocycles as kinase inhibitors,particularly Met kinase,for treating cancer[P].WO:2005117867A2,2005-12-15.
  • 9张园园,罗仕忠,詹妍,侯若彤,吴凯群,王玉良.2,3,5-三溴-4′-硝基-4,2′-双羟基二苯醚的合成及其抑菌活性研究[J].化学研究与应用,2007,19(7):820-822. 被引量:4
  • 10吴萍,王葆生,孙晶,颜朝国.微波辐射促进的甲酰基二芳基醚的合成[J].河南大学学报(自然科学版),2006,36(4):55-57. 被引量:1

二级参考文献37

共引文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部