31例肉芽肿性乳腺炎的临床诊治分析

Analysis of clinical diagnosis and treatment for granulomatous mastitis in 31 cases

目的探讨肉芽肿性乳腺炎的病因,临床特点,以及诊治方法 ,指导临床实践。方法收集我院2007年6月至2010年1月间住院治疗的31例肉芽肿性乳腺炎。分析其临床、病理特点,以及诊治经过。结果在该研究组中30例(97%)患者有生育史,且11例(35%)有积乳病史。85%(25/29)在产后6年内发病,中位发病间隔期为3年。79%(22/28)不伴有白细胞计数的升高。病理检查病灶为多灶性。93%(29/31)的病例通过I期或II期手术切除病灶得以治愈。结论使用抗生素联合皮质类固醇激素治疗可控制肉芽肿性胰腺炎的病情进展。病灶切除术是根治该病主要方法 。

Objective To investigate the causes,clinical features and diagnosis,therapeutic methods of granulomatous mastitis.Methods From June 2007 to January 2010,31 cases with granulomatous mastitis were collected.The patients＇ clinical,pathological feature and diagnosis,therapeutic course were analyzed retrospectively.Results In this group,30 cases（97%） had childbearing history and 11 cases（35%） had galactostasis history.Morbidities of 85%（25/29） were in the postpartum within 6 years.The interval period of median onset was in 3 years.The white blood cell count was not increased in 79% cases（22/28）.Pathological examination showed that lesions were multiple.Ninety three percent cases（29/31） were cured by primary or secondary resection foci.Conclusion Application of antibiotics combined with corticosteroid could control the progress of the disease.Resection foci are a principal measure to treat such case.