西甲硅油联合思密达治疗小儿急性腹泻疗效观察

Observation on the therapeutic effect of simethicone combined with smectite for treatment of pediatric acute diarrhea

目的探讨西甲硅油与思密达治疗小儿急性腹泻的疗效。方法将100例小儿急性腹泻患儿随机分为治疗组和对照组,每组各50例,均给予口服思密达和对症治疗,治疗组在此基础上加用西甲硅油,比较两组疗效。结果治疗组和对照组的总有效率分别为94%和72%,平均止泻时间为(48.15±5.24)h和(86.16±17.89)h,差异有统计学意义(P<0.01)。结论西甲硅油联合思密达治疗小儿急性腹泻疗效好,可以在临床中推广应用。

Objective To observe the effect of simethieone combined with smectite for treatment of pediatric acute diarrhea. Methods One hundred children with acute diarrhea were randomly divided into two groups, treatment group and control group（ n = 50/group）. All the cases in both groups were treated with conventional oral administration of smectite pow- der and symptomatic treatment. The simethieone was added in the treatment group. Compared the outcomes between the two groups. Results The total effective rate of 94% in the treatment group was higher than that of 72% in the control group. The mean time of diarrhea was （48.15 ± 5.24） h and （86. 16 ± 17. 89） h respectively in the treatment group and the control group. The mean time of diarrhea was significantly different between the two groups （ P 〈 0. 01 ）. Conclusions Simethicone combined with smectite was an effective treatment for pediatric acute diarrhea and was worth for clinical use.