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猪繁殖与呼吸障碍综合征病毒结构蛋白的研究进展与应用 被引量:3

Research Progress and Application of the Structural Proteins of Porcine Reproductive and Respiratory Syndrome (PRRS) Virus
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摘要 猪繁殖与呼吸障碍综合征病毒(PRRSV)属于动脉炎病毒科的单股正义RNA病毒。病毒基因组共有15kb,编码RNA复制酶(ORF1a和ORF1b)、糖基化蛋白(GP2-GP5)、基膜蛋白M(ORF6)和核衣壳蛋白N(ORF7)。其中每一个PRRSV的结构蛋白在病毒的感染及免疫原性等的作用均不相同。笔者对PRRSV结构蛋白最新的研究进展及应用进行综述。 Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-strand RNA virus that belongs to the Arteriviridae family. The genomic RNA is approximately 15 kb. The genome encodes the RNA replicase (ORF1a and ORF1b), the glycoprotein (GP2 to GP5), the integral membrane protein M (ORF6), and the nucleocapsid protein N (ORF7). Each of the PRRSV structural proteins has a distinct role in virus infection, immune response etc. This thesis sums up the research and application of the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus.
出处 《中国农学通报》 CSCD 北大核心 2010年第23期1-6,共6页 Chinese Agricultural Science Bulletin
基金 甘肃科技重大专项(0801NKDA034)
关键词 糖基化蛋白 免疫原性 小结构蛋白 异源二聚体 glycoprotein immunogenicity minor structural protein heterodimers
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