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孕妇血浆中胎儿DNA检测在产前诊断中的应用

Detection of fetal DNA in maternal plasma for prenatal diagnosis
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摘要 孕妇外周血中可检测到胎儿DNA,并随着孕周增加,胎儿DNA浓度也增加。胎儿DNA序列分析已成功地应用于产前诊断的临床实践中,可用于胎儿性别鉴定、血型分析、单基因遗传病及各种病理妊娠的诊断。相信在未来的几年内,应用胎儿DNA测定进行非侵入性产前诊断将有更大的实质性进展。 Fetal DNA can be detected in maternal blood and the concentration increases with the gestation.The analysis of fetal DNA sequence has been successfully used in clinical work,for example,sex determination,Rhesus status,single gene disorder and many pregnancy-related diseases.It is believed that in the near future,better development will be made in non-invasive prenatal diagnosis with fetal DNA analysis.
作者 彭文 王谢桐
机构地区 山东大学附属省立医院妇产科
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2010年第12期914-916,共3页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 孕妇血 胎儿DNA 非侵入产前诊断 maternal blood fetal DNA non-invasive prenatal diagnosis
分类号 R71 [医药卫生—妇产科学]
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参考文献10

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中国实用妇科与产科杂志
2010年 第12期

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