二期梅毒误诊2例报道

A report on two cases of misdiagnosed secondary syphilis

目的:报告2例二期梅毒误诊病例,二期梅毒皮损多种多样,可有斑疹、丘疹、脓疱疹、斑块、结节等,常易误诊为一般的皮肤病而延误治疗。方法:2例患者查血快速血浆反应素环状卡片试验(RPR)均〉1∶8(+),梅毒螺旋体血凝试验(TPHA)(+)。结果:病理检查,表皮增生,真皮层可见密集混合性炎症细胞浸润,其中大量浆细胞。结论:诊断为二期梅毒。

Objectives：To report on two cases of misdiagnosed secondary syphilis. The skin lesion caused by secondary syphilis may have different manifestations, such as macula, papula, pustular eruption, plaque, protuberance, etc. Therefore, it is prone to be misdiagnosed as common skin disease, resulting in the delayed treatment. Both of the two cases showed the value great than 1∶8（＋）in the rapid plasma reagin circle card Test （RPR）, and positive results in treponema pallidum hemagglutination assay （TPHA）. Pathological test revealed cutis hyperplasia, and dense mixed inflammatory corpuscle soakage, which contains a great number of plasma cells and is visible on connective tissue layer. The two cases should be diagnosed as secondary syphilis.