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非小细胞肺癌中组织蛋白酶B表达及与生物学行为的关系 被引量:3

非小细胞肺癌中组织蛋白酶B表达及与生物学行为的关系
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摘要 目的探讨Cathepsin B在非小细胞肺癌中的表达及与生物学行为的关系。方法采用免疫组化S-P法检测100例NSCLC组织Cath B的表达。结果 CB在NSCLC表达与淋巴结转移相关(P<0.05)。结论 CB在NSCLC中高表达,在NSCLC的发生、发展中起重要的作用,与NSCLC的淋巴结转移有关。 Objective To discuss cathepsin B(CB) expression in NSCLC and its relationship with biological behaviour. Methods Using immunohistochemistry (S-P method) to detect CB in NSCLC (n= 100). Results the relationship between CB expression and lymph node metastasis is significant( P 〈0. 05). Conclusions CB increases in NSCLC,plays an important role in occurrence and progression of NSCLC and is related to lymph node metastasis.
出处 《当代医学》 2010年第34期32-34,共3页 Contemporary Medicine
关键词 非小细胞肺癌 组织蛋白酶B 浸润和转移 NSCLC CB Invasion and metastasis
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