床边连续性静脉-静脉血液透析滤过治疗重症急性肾功能衰竭临床疗效研究

Clinical Effect of Bedside Continuous Venovenous Hemodiafiltration to Treat Severe Acute Renal Failure

目的:比较床边连续性静脉-静脉血液透析滤过(CVVHDF)与间歇性血液透析(IHD)治疗重症急性肾功能衰竭疗效。方法:收集我院2008年1月-2010年1月重症急性肾功能衰竭病例56例,分成两组,各28例,一组行床边连续性静脉-静脉血液透析滤过治疗,另一组采用间歇性血液透析。结果:CVVHDF治疗后尿素氮、肌酐、尿酸、K+、Na+、pH值较治疗前有显著的改善(P<0.05),CVVHDF与IHD相比对血压的影响更小(P<0.05)。CVVHDF组有效率78.5%(22例)高于IHD组有效率53.6%(15例)(P<0.05)。结论:CVVHDF治疗的效果优于IHD,能改善重症急性肾功能衰竭的预后。

Objective： To observe the effect of continuous venovenous hemodiafiltration to treat severe acute renal failure.Methods：To collect fifty-six severe acute renal failure cases from January 2008 to January 2010 were divided into two groups.Each group had 28 cases.One group was treated with bedside continuous venovenous hemodiafiltration,the other was treated with intermittent hemodialysis.Results： In CVVHDF group,the serum creatinine,urea nitrogen,uric acid,pH,K＋,Na＋,had notable improvement（P0.05）.The effect on blood pressure in CVVHDF group compared with IHD group was smaller（P0.05）.The effective rate（78.5%）in CVVHDF group was better than the IHD group（53.6%）（P0.05）.Conclusion：The cure effect in CVVHDF group is better than the IHD group,and it can improve prognosis in severe acute renal failure patients.