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erbtM/HER4在宫颈癌组织中的表达研究

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摘要 目的检测第四人体表皮生长因子受体(HER4)在宫颈癌组织中的表达,探讨HER4过度表达与宫颈癌临床病理的关系。方法采用免疫组织化学的方法检测60例宫颈癌组织中HER4的表达。结果宫颈癌组织中HER4的过度表达率为76.67%。宫颈癌中HER4的过度表达仅与盆腔淋巴结转移、宫旁浸润及TNM分期相关。结论erbB4基因是宫颈癌生长的一个调控基因,干预HER4蛋白的过度表达可能是治疗宫颈癌的有效方法。
出处 《中国基层医药》 CAS 2010年第22期3075-3076,共2页 Chinese Journal of Primary Medicine and Pharmacy
基金 基金项目:浙江省宁波市卫生局资助课题(2002057)
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