摘要
目的:用正交设计法优选青皮挥发油β-环糊精包合工艺的最佳条件。方法:用饱和水溶液超声法。结果:最佳工艺条件是油与β-环糊精之比为1∶8(mL.g-1),其次是乙醇体积分数为90%,超声时间30 min,超声时水温为40℃~45℃。结论:β-环糊精不同用量是影响青皮挥发油包合效果的主要因素,该工艺方法简单,流程短,适合工业化生产。
Objective : To optimize the best β-cyclodextrin including technology conditions of volatile oil from Pericarpium Cirri Reticulatae Viride by orthogonal design. Method:The saturated aqueous solution-ultrasound method was used. Result:The optimum preparation conditions were established as follows:the proportion of volatile oil to β-cyclodextrin was 1 : 8 ( mL. g ^- 1 ) , The concentration of alcohol was 90 % , The ultrasonic time was 30 min, The water temperature was at 40 ℃-45 ℃. Conclusion:The different usage of β-cyclodextrin is the principal factor that in- fluence the inclusion effect of volatile oil from Pericarpium Citri Reticulatae Viride,the method of this technology is simple, and the technological process is short, it is suitable for commercial process.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第18期36-38,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
中国中医科学院自主选题项目(ZZ2007003)
关键词
青皮
挥发油
Β-环糊精
包合物
正交设计法
气相色谱·质谱联用
Pericarpium Citri Reticulatae Viride
volatile oil
β-cyclodextrin
including compound
orthogohal design
GC-MS