凉血解毒活血颗粒抗炎作用的研究

Experimental Studies on Anti-inflammatory Effect of Liangxue Jiedu Huoxue Granules

目的:观察凉血解毒活血颗粒的抗炎作用。方法:分别采用蛋清致大鼠足趾肿胀法和醋酸致小鼠腹腔毛细血管通透性增高的方法,观察凉血解毒活血颗粒的抗炎作用。结果:①凉血解毒活血颗粒可以明显的减轻蛋清所致的大鼠足趾肿胀,(P<0.05);②凉血解毒活血颗粒可显著抑制0.6%醋酸所致的小鼠腹腔毛细血管通透性的增高,与模型组比较有显著的统计学意义(P<0.01)。结论:凉血解毒活血颗粒具有良好的抗炎作用。

Objective： To study the anti-inflammatory effects of the Liangxue Jiedu Huoxue Granules. Method：The anti-inflammatory effect of Liangxue Jiedu Huoxue Granules was observed on pathological model with increasing vascular permeability induced by acetic acid in mice and the model of paw edema caused by egg white in rats. Result： The Liangxue Jiedu Huoxue Granules could significantly decrease the degree of paw edema caused by egg white in rats （P 〈 0.05） and markly inhibit the degree of the increase in permeability of the capillaries （P 〈 0.01 ）. Conclusion ： The Liangxue Jiedu Huoxue Granules has significant action of anti-inflammation.