大承气汤加味治疗急性重症胰腺炎36例

Analysis of Therapeutic Effect on 36 Cases of Severe Acute Pancreatitis Treated with Modified Dachengqi Tang

目的:观察大承气汤加味治疗急性重症胰腺炎的临床疗效。方法:36例急性重症胰腺炎患者,随机分为两组,对照组单纯予以西药常规治疗,治疗组在常规治疗的基础上应用大承气汤加味治疗,比较两组患者的临床疗效、相关测定指标以及不良反应情况。结果:治疗组总有效率88.9%,对照组总有效率66.7%,治疗组疗效明显高于对照组(P<0.05);与对照组治疗后相比,治疗组降低血、尿淀粉酶和C反应蛋白(CRP)的作用更明显(P<0.01)。两组体温恢复正常时间,腹痛缓解时间,血尿淀粉酶恢复正常时间,白细胞恢复正常时间比较,治疗组均短于对照组(P<0.01)。治疗组不良反应明显低于对照组。结论:采用大承气汤加味治疗急性重症胰腺炎治疗效果优于单纯西药常规治疗。

Objective：To observe clinical effect of treating severe acute pancreatitis with modified Dachengqi Tang. Method ：Thirty-six cases patients with severe acute pancreatitis were randomly divided into two groups. The control group was treated with conventional medical treatment, and the treatment group was treated with modified Dachengqi Tang based on the control group. The clinical effect, related parameters and adverse reaction were observed for control group and treatment group. Result：The total effective rate of the treatment group and the control group was 88.9% and 66.7% respectively, the clinical effect in the treatment group was significantly higher than that of the control group （P 〈 0. 05 ）. Combined with control group, serum/uric amylase and reactive protein decreased significantly（P 〈0. 01 ~ P 〈 0. 05）after treatment, serum/uric amylase and reactive protein decreased significantly before treatment in this group, especially in the treatment group. There was a significant difference （P 〈0. 01）. The time for body temperature returned to normal, abdominal pain relief, serum/uric amylase returned to normal and leukocyte returned to normal have significant differences （P 〈 0. 05）. All the times were shorter for the treatment group. Adverse reaction in the treatment group was lower than that of the control group. Conclusion： The modified Dachengql Tang for treatment of severe acute pancreatitis is better than conventional medical treatment.