探讨门诊处方的不合理用药

Unreasonable of Outpatient Prescription Drugs

目的:分析我院门诊处方不合理使用情况,促进临床合理用药。方法:随机抽查我院2009年7月至12月门诊西药处方1万张,根据药品说明书、临床药理学知识以及公开出版的文献资料,对不合理处方进行分析,并加以分类统计。结果:不合理处方总计381张,分别在溶媒选用不当、不符合药代动力学规律、药理拮抗、重复用药、选药不合理、毒性相加及理化性状改变方面存在问题。结论:我院门诊用药基本合理,但仍存在一定问题,同时希望临床医师与药师共同加强药学知识的学习。

Objective： To analyze the unreasonable use of outpatient prescription to guide clinical rational drug use. Method ： Randomly check of 10,000 outpatient prescription in our hospital during July 2009 to December 2009, then analyze and classified statistics according to the instruetions medicines, clinical pharmacology knowledge, and the published literature on the unreasonable prescription. Result： The total of 381 prescriptions was unreasonable. Some of reason was inappropriate choice of solvent, some was that the law did not meet the pharmacokinetics, some was pharmacological antagonism, some was duplicate medication, some was unreasonable to select drug, the others was adding of toxicity and changes in physical and chemical properties. Conclusion： The use of drugs is basically reasonable in our hospital, but we found a few problems. So we hope that physicians and pharmacists to strengthen the pharmaceutical knowledge in common.