血管运动性鼻炎患者鼻通气功能的评估

Evaluation of nasal patency in patients with vasomotor rhinitis

目的 检测血管运动性鼻炎患者的鼻通气功能,分析其与主观症状的相关性,并与健康对照组进行比较.方法 选择血管运动性鼻炎患者105例,健康对照组成人71例.采用鼻阻力测量获得压力-流速曲线,进而得到75 Pa和150 Pa下鼻腔总阻力值.采用鼻声反射测量应用鼻用缩血管药物前后的面积-距离曲线,进而得到鼻腔最小横截面积,计算鼻腔充血指数.对比两组研究对象各项鼻阻力和鼻声反射测量指标,分析血管运动性鼻炎患者主观症状评分与鼻通气功能指标间的相关性.采用SPSS 16.0软件进行统计分析.结果 血管运动性鼻炎患者鼻阻力、鼻声反射指标与各种鼻部症状间的相关性分析均无统计学意义（P值均〉0.05）.收缩前后的鼻腔最小横截面积在两组间差异未见统计学意义（Z值分别为-1.541、-0.626,P值均〉0.05）;鼻腔充血指数在两组间差异有统计学意义（Z=-2.707,P〈0.05）.75 Pa下鼻总阻力值在两组间差异有统计学意义（Z=-4.334,P〈0.05）;150 Pa下鼻总阻力值在两组间差异无统计学意义（Z=-1.314,P〉0.05）.结论 血管运动性鼻炎患者主观症状与客观鼻生理功能检测结果 间无相关性,在诊疗过程中需全面综合评价患者的主观症状和客观检测结果 .

Objective To measure the nasal patency in patients with vasomotor rhinitis （VMR）and healthy controls and to assess its correlation with visual analogue scale （VAS）. Methods A total of 105 patients with VMR and 71 healthy controls were included in this study. By using nasal rhinomanometry,the pressure-flow curve and got total nasal resistances of 75 Pa and 150 Pa were measured. By means of acoustic rhinometry, the area-distance curve before and after using nasal vasoconstrictor substance was obtained, got the nasal minimum cross-sectional area （MCA）, then calculated nasal congestion index （NCI）. The outcomes of nasal resistance and acoustic rhinometry in two groups were compared. The correlation between VAS and nasal patency of VMR was evaluated. Results The correlation between the outcomes with nasal resistance and acoustic rhinometry and VAS of nasal symptom showed no statistical significance in VMR patients （all P 〉 0. 05）. MCA before and after decongestion showed no difference （Z value were - 1. 541 and - 0. 626, each P 〉 0. 05）, NCI had statistic differences in two groups （Z =- 2. 707, P 〈 0. 05）. Nasal resistance of 75 Pa had statistic differences in two groups （Z = - 4. 334, P 〈0. 05）, 150 Pa showed no difference （Z = - 1.314, P 〉 0. 05）. Conclusions Vasomotor rhinitis is one of the most common non-allergic rhinitis. Subjective symptoms has no correlation with objective nasal patency tests. In clinical practice, comprehensive evaluation of subjective symptoms and objective test results of the patient is required.