胃角溃疡病理特点及幽门螺旋杆菌感染127例分析

目的:探讨胃角溃疡患者的病理特点及幽门螺旋杆菌(Hp)感染率。方法:对2004年7月～2009年12月胃镜诊断为胃角溃疡的127例患者行快速尿素酶试验和14C-呼气试验,并行镜下取组织标本活检和了解胃角溃疡病理特点及HP感染率。结果:本组127例胃角溃疡病例中,有36例经病理证实为恶性溃疡,癌变率27.6%;Hp阳性105例,感染率82.7%。在36例恶性胃角溃疡中,Hp阳性26例,感染率72.2%。结论:胃角溃疡癌变率较高,且与幽门螺旋杆菌感染相关。

Objective：To investigate the clinicopathological characters of angular ulcer and the infection rate of Helicobacter Pylori （ Hp ）. Methods ： 127 patients with angular ulcer, who had been diagnosed by gastroscope, were performed by rapid urease test C - urea breath test, tissue biopsy specimen were obtained under endoscopy and to understand the clinicopathological characters of angular ulcer and the infection rate of Helicobacter Pylori （Hp）. Result： Out of the 127 patients with angular ulcer, 36 were confirmed as malignant ulcer by Pathology, in 27.5% of eases; 105 were tested Hp positive,in 82.7% of cases. 26 were tested Hp positive in these 36 patients with malignant ulcer, the infection rate was 72. 2%. Conclusions：The canceration rate of angular ulcer has a strong correlation with the infection rate of Helicobacter Pylori （Hp）.