急性CO中毒迟发性脑病的MRI表现

MRI manifestations of delayed encephalopathy after acute carbon monoxide poisoning

目的:探讨急性CO中毒迟发性脑病(DEACMP)的MRI特征。方法:回顾性分析21例急性CO中毒迟发性脑病患者的MRI和临床资料。结果:急性CO中毒迟发性脑病MRI表现可分为3种:①神经核团受累:21例,典型表现为双侧苍白球对称性的长T1、长T2信号;②脑白质受累:11例,表现为双侧大脑半球白质对称云絮状长T1、长T2信号,胼胝体常受累;③皮层受累:6例,表现为双侧大脑半球皮层对称性弥漫长T1、长T2信号。结论:急性CO中毒迟发性脑病MRI表现有一定特征性,MRI对急性CO中毒迟发性脑病的诊断、鉴别诊断、判断预后具有重要价值。

Objective： To investigate the MRI features of delayed encephalopathy after acute carbon monoxide poisoning（ DEACMP） . Methods： MRI and clinical data of 21 cases with DEACMP were studied retrospectively. Results： DEACMP were classified into three types according to MRI findings ： ① neural nuclei involvement： 21 cases,symmetrical long T1 and long T2 signal intensity foci in bilateral globus pallidus; ② white matter involvement： 11 cases,symmetrical,cloudy and blurred lesions of long T1 and long T2 signal intensity appeared in the white matters. Corpus callosum was often involved. ③ brain cortex involvement： 6 cases,symmetrical,diffuse long T1 and long T2 signal intensity appeared in the cortex. Conclusion： MRI is valuable in the diagnosis,differentiation diagnosis and prediction of prognosis of DEACMP.