老年原发性高血压患者动态血压参数与前列腺体积的相关性

Correlation between parameters of ambulatory blood pressure monitoring and prostatic volume in elderly men with essential hypertension

目的 探讨老年原发性高血压患者动态血压参数与前列腺体积的相关性. 方法 选择2007年3月至2009年12月在我科就诊的老年男性原发性高血压患者131例,其中良性前列腺增生（BPH）组102例,非BPH组（NBPH）29例,所有患者均进行动态血压监测及前列腺超声检查,计算前列腺体积;应用SSPS13.0软件包进行统计分析,对两组前列腺体积进行均数检验,应用Spearman回归系数法对所有患者的动态血压参数与前列腺体积进行相关性检验. 结果 （1）BPH组的夜间最大平均动脉压（MAP）（104.7±12.0）mm Hg,高于NBPH组（99.6±10.1）mm Hg,差异有统计学意义（t=2.088,P=0.039）;（2）动态血压参数中全天最大MAP（r=0.184,P=0.035）、白天最大MAP（r=0.183,P=0.037）、夜间最大MAP（r=0.181,P=0.040）与前列体积具有相关性.结论老年原发性高血压患者动态血压参数中的最大MAP与前列腺体积具有相关性.

Objective To explore the correlation between the parameters of ambulatory blood pressure monitoring （ABPM） and prostatic volume in elderly patients with essential hypertension.Methods The 131 elderly patients with essential hypertension from March 2007 to December 2009 were enrolled in this study, including 102 benign prostatic hyperplasia （BPH） patients and 29 nonBPH （NBPH） patients. All patients underwent ABPM and ultrasound examination of prostate.Prostatic volumes （PV） were calculated and were compared between BPH group and NBPH group.Correlation between parameters of ABPM and PV was analyzed. Results （1）The maximal mean artery pressure （MAPmax） at night was higher in BPH group than in NBPH group [（ 104.7 ± 12. 0）mm Hg vs. （99.6± 10. 1） mm Hg, P= 0.039]. （2）There were correlations between PV and MAPmax in all-day （r=0. 184, P=0. 035）, MAPmax at daytime （r=0. 183, P=0. 037）, MAPmax at night （r=0. 181, P=0. 040）, respectively. Conclusions MAPmax of ABPM may be associated with PV in elderly patients with essential hypertension.