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人冠状病毒NL63棘突蛋白的研究进展 被引量：2

Progress on Spike Protein of Human Coronavirus NL63
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摘要 20世纪60年代以前,人们普遍认为只有2种人冠状病毒(HCoV)HCoV-229E和HCoV-OC43感染人类,2002～2003年出现的由SARS-CoV引发的严重急性呼吸综合征(SARS)的流行使人冠状病毒又一次成为研究的焦点,2004年又发现了一种新的人冠状病毒HCoV-NL63。在此,主要就HCoV-NL63,特别是其主要结构蛋白——棘突蛋白的研究进展做一简要综述。 From the mid-1960s onwards,it was believed that only two human coronavirus（HCoV） species infect humans,HCoV-229E and HCoV-OC43.Then,2002～2003,a novel member of the coronavirus family was introduced into the human population,SARS-CoV,causing severe acute respiratory syndrome（SARS） which has once again made coronavirus become the focus of virus research.Then HCoV-NL63 was identified in 2004.Here we presented an overview on this novel coronavirus,especially HCoV-NL63 spike protein.
作者 赵国霞 高基民 谭文杰
机构地区 中国疾病预防控制中心病毒病预防控制所 温州医学院
出处 《生物技术通讯》 CAS 2010年第6期879-882,共4页 Letters in Biotechnology
基金 国家高技术研究发展计划(2007AA02Z464) 传染病重大专项(2008ZX10004-014)
关键词 人冠状病毒 HCOV-NL63 棘突蛋白 human coronavirus HCoV-NL63 spike protein
分类号 R373.1 [医药卫生—病原生物学]
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参考文献25

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同被引文献15

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生物技术通讯
2010年 第6期

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