原发性系统性淀粉样变性并发多发性骨髓瘤

Primary systemic amyloidosis accompanied by multiple myeloma:a case report

报告1例原发性系统性淀粉样变性并发多发性骨髓瘤。患者男,68岁。表现为紫癜、瘀斑、斑块的原发性系统性淀粉样变性,患者曾被多次误诊,最终确诊为原发性系统性淀粉样变性并发多发性骨髓瘤。

Systemic amyloidosis （SA） is a systemic metabolic disorder with extensive deposition of amyloid protein in skin, inter- nal organs and mucous. Skin involvement occurs in 40% of SA patients and many of them consult dermatologists first. Here a case is presented with purpura, ecchymosis and plaque which had been misdiagnosed for many times and the diagnosis of primary systemic amyloidosis accompanied by multiple myeloma was confirmed in the end.