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肺泡液体清除率与囊性纤维跨膜电导调节因子氯通道的关系

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摘要 急性肺损伤与急性呼吸窘迫综合征是同一疾病的不同发展阶段,肺水肿是两者的主要病理改变之一。肺水肿与肺泡液体清除率之间存在密切关系,提高肺泡液体清除率可以加快肺泡水肿液体的吸收。大量研究表明,上皮钠通道和囊性纤维跨膜电导调节因子氯通道是参与肺泡水肿液体清除过程的重要通道,它们的缺失或功能障碍会导致肺泡水肿液体的清除受阻。本文就肺泡液体清除机制及上述两种通道在这一过程中所发挥的作用做一阐述。
出处 《心脏杂志》 CAS 2010年第6期940-942,946,共4页 Chinese Heart Journal
基金 陕西省社会发展科技攻关项目资助(2009K13-01)
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