摘要
磺酰胺类化合物具有广泛的生物活性,临床上使用含有磺酰胺结构片断的药物众多,其研究与开发备受关注,日益活跃,发展十分迅速。文中综述了含磺酰胺结构类化合物在抗菌、抗真菌、抗病毒、抗寄生虫、抗结核等领域的研究与开发进展。
Sulfamide compounds exhibit a broad-spectrum of biological activities and various types of sulfamide drugs have extensively been used in clinic.Much attention has increasingly been paid toward the research and development of sulfonamides as drugs,and the progress is quite fast.This article reviewed recent advances in the research and development of sulfamide compounds as antibacterial,antifungal,antiviral,antiparasitic and anti-tuberculosis agents.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2010年第22期2050-2059,共10页
Chinese Journal of New Drugs
基金
重庆市自然科学基金(CSTC2007BB5369
2006BB4341)
西南大学人才引进基金(SWUB2006018)
西南大学高新技术培育基金(XSGX0602)
关键词
磺酰胺
抗微生物
抗菌
抗病毒
抗真菌
抗寄生虫
抗结核
sulfamide
antimicrobial
antibacterial
antiviral
antifungal
antiparasitic
anti-tuberculosis