丝裂霉素C联合可调整缝线小梁切除术治疗青光眼疗效观察

Clinical observation of mitomycin C with adjustable suture in trabeculectomy in the treatment of the glaucoma

目的:探讨丝裂霉素C联合可调整缝线小梁切除术治疗青光眼的临床疗效。方法:将2008年2月～2010年6月收治的青光眼患者160例随机分为治疗组(80例)和常规治疗组(80例),观察两组疗效及并发症。结果:两组治疗前、后眼压比较,差异无统计学意义(P>0.05);两组并发症、浅前房分度比较,差异有统计学意义(P<0.05)。结论:应用丝裂霉素C联合可调整缝线小梁切除术治疗青光眼,可主动调节青光眼滤过手术的滤过量,防止滤过道粘连阻塞,有效地控制眼压水平,最大限度地减少术后并发症,提高青光眼的手术成功率。

Objective： To explore the clinical efficacy of with adjustable suture in trabeculectomy in the treatment of the glaucoma. Methods： From February 2008 to June 2010, 160 cases of glaucoma patients were randomly divided into treatment group （80 cases） and conventional therapy group （80 cases）, the efficacy and complications were observed. Results： Before and after treatment, there was no significant difference about IOP （P〉0.05）; there were significant differences on the complications, shallow anterior chamber dividing in two groups （P〈0.05）. Conclusion： Mitomycin C with adjustable suture in trabeculectomy in the treatment of the glaucoma, can take the initiative to adjust the amount glaucoma filtration surgery to prevent filtration road adhesion obstruction, and can effectively control the level of intraocular pressure, reduce complications and improve the success rate of glaucoma surgery.