超广谱β-内酰胺酶肺炎克雷伯菌的检测及耐药性分析

Detection and drug resistance of extended spectrum β-lactamases in Klebsiella pneumoniae

目的:了解医院超广谱β-内酰胺酶(ESBLs)肺炎克雷伯菌的耐药特点,以指导临床用药。方法:采用常规方法进行细菌鉴定,K-B纸片扩散法进行药敏试验,按CLSI标准进行确证试验。结果:从152肺炎克雷伯菌中检出超广谱β-内酰胺酶肺炎克雷伯菌55株,检出率为36.2%,且耐药性比较复杂。结论:超广谱β-内酰胺酶肺炎克雷伯菌在临床上检出率较高,多药耐药明显,须引起临床重视。

Objective： To investigate the drug resistance features of extended spectrum β-lactalnases （ESBLs） Klebsiella pneumoniae and provide the gist for clinical therapy. Methods： Identification of bacteria by conventional methods, durgsensitivity test was performed by K-B methods, confirulatol7 test by CLSI standards. Results： 55 samples spectrum β-lactamases in Klebsiella pneumoniae were detected among 152 samples Klebsiella pneumoniae, the detection rate was 36.2%, and resistance was more complicated. Conclusion： Extended spectrum β-lactamases in Klebsiella pneumoniae is higher in the clinical detection, with multidrug resistance obvious. It must be paid attention.