原发性高血压30例的心率变异性及其昼夜节律分析

Time domain in heart rate variability and its circadian rhythm in patients with essential hypertension

目的：探讨原发性高血压患者心率变异性及其昼夜节律变化的规律。方法：通过记录30例Ⅰ、Ⅱ期原发性高血压患者，30例正常血压者（对照组）的24小时动态心电图，分析24小时内每1小时的心率变异性（HRV）的时域指标（pNN50、rMSSD、SD）。结果：高血压病组的各项NRV指标均较对照组低（P＜0．05，P＜0．01），昼夜节律性明显减弱。结论：高血压病患者植物神经调节异常，HRV及昼夜节律均减弱。

Objective: To study alternations in heart rate variability (HRV) and its circadian rhythm in patientswith essential hypertension (EH). Methods: 24 hours Holier electrocardiogram (HEM) were recorded in 30 patientswith EH and in 30 normotensive subjects. Altercations in HRV indexes of time domian (pNN 50, rMSSD, SD) wereanalyzed. Results: All HRV indexes in EH group decreased than those in control group (P<0. 05, P<0. 01) withobviously weaked circadian rhythm. Conclusion: Patients with EH have abnormal modulation of the autonomicnervous system, both HRV and ciraedian rhythm decreased in them.