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阿托伐他汀对心肌梗死患者血脂水平的影响及疗效观察 被引量:2

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摘要 目的观察在常规治疗的基础上合用阿托伐他汀治疗心肌梗死的疗效,并探讨其对心肌梗死患者血脂水平的影响。方法 120例入选的我院住院治疗的心肌梗死患者随机分为观察组和对照组各60例,两组均给予吸氧、止痛、扩冠、抗心律失常、溶栓、抗凝等常规治疗,观察组在常规治疗基础上加阿托伐他汀20mg,每日一次,疗程3个月。观察比较两组的疗效及对心肌梗死患者血脂水平的影响。结果观察组与对照组的TC、TG、LDL-C水平治疗3个月后检测显示,与本组治疗前比较均明显降低,差异有统计学意义(P<0.01)。观察组的TC、TG、LDL-C水平降低的水平与对照组比较,差异也有统计学意义(P<0.01)。但观察组的HDL-C的水平治疗后较治疗前明显升高,但升高的水平与对照组比较,差异不显著。观察组的心率、7d内恶性心律失常发生率及死亡率均明显低于对照组,差异有统计学意义(P<0.05)。观察组有2例出现一过性便秘、1例出现肌肉疼痛,停药后自行缓解;对照组未见不良反应发生。结论在常规治疗的基础上加用阿托伐他汀可以明显降低患者的血脂水平,降低死亡率,并发症少,值得临床推广。
作者 罗志英
出处 《中国现代医生》 2010年第34期30-31,共2页 China Modern Doctor
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