活血通络方浴足联合弥可保治疗2型糖尿病下肢周围神经病变的临床观察

Clinical Observation of Huoxue Tongluo Decoction Foot Bathing Combined with Oral Use of Mecobalamin for Low-limb Peripheral Neuropathy in Type 2 Diabetes

目的:观察自拟活血通络方浴足联合弥可保治疗2型糖尿病下肢周围神经病变的临床疗效。方法:将60例患者随机分为治疗组和对照组各30例,均在西药降血糖基本达标的基础上,对照组单纯口服弥可保,治疗组在口服弥可保的基础上加用自拟活血通络方浴足,均治疗8周。结果:临床总有效率治疗组为96.67%,对照组为76.67%,2组比较,差异有显著性意义(P<0.05)。2组治疗后腓神经感觉传导速度比较,差异有显著性意义(P<0.05)。结论:活血通络方浴足联合弥可保治疗2型糖尿病下肢周围神经病变疗效优于单独使用弥可保,是治疗该病的有效方法之一。

Objective： To observe the clinical effect of Huoxue Tongluo Decoction foot bathing combined with oral use of mecobalamin for treating low-limb peripheral neuropathy in type 2 diabetes. Methods： Sixty patients were equally divided into the treatment group and the control group, Both groups were given the hypoglycemic for decreasing blood glucose to the targeting level. The control group was given oral use of mecobalamin, while the treatment group was treated with Huoxue Tongtuo Decoction foot bathing additionally. The treatment of two groups lasted 8 consecutive weeks. Results： The total effec- tive rate was 96.67% in the treatment group, and 76.67% in the control group, the difference being significant （P 〈 0.05）. After treatment, the motor nerve conduction velocity of sural was remarkably improved in the treatment group （P 〈 0.05 compared with that in the control group）. Conclusion. The efficacy of Huoxue Tongluo Decoction foot bathing combined with oral use of mecobalamin proves to be superior to mecobalamin alone in the treatment of low-limb peripheral neuropathy in type 2 diabetes.