摘要
目的:探讨光学相干断层成像术(OCT)与超声角膜测厚仪测量角膜厚度的统计学差异及临床意义。方法:选取2010-07/09在我院屈光矫治中心就诊的近视患者102例199眼,分别行OCT及超声测厚法测量角膜厚度,经统计学检验后进行分析。结果:患者199眼经OCT所得结果为532.478±29.49μm,超声测厚仪所得结果为541.47±29.00μm,行配对t检验(t=14.805,P=0.000),认为两种测量方法结果的差异有统计学意义。进一步以超声测厚结果为标准将角膜厚度分4组进行配对t检验,角膜厚度≤500μm时,OCT测量角膜厚度值(479.07±11.57μm)与超声结果(486.47±7.24μm)差异有统计学意义(P=0.002);500μm<角膜厚度≤550μm时,OCT测量角膜厚度值(520.34±12.56μm)与超声结果(529.16±12.41μm)差异有统计学意义(P=0.000);550μm<角膜厚度≤600μm时,OCT测量角膜厚度值(554.99±14.02μm)与超声结果(563.93±10.11μm)差异有统计学意义(P=0.000);角膜厚度(600μm时,因为例数太少未作比较。结论:传统的超声测厚与OCT对角膜测厚结果有一定差异,并具统计学意义,但在临床意义上二者仍有较好的相符性,可以作为准分子手术前的评估参考。
AIM:To investigate the clinical significance of corneal thickness measurement difference between optical coherence tomography (OCT) and corneal pachymeter.
METHODS:The clinical data of corneal thickness in 102 cases 199 eyes measured by ultrasonic corneal hymeter and OCT were analyzed by statistical test.
RESULTS: The thicknesses were 532.478±29.49μm and 541.47±29.00μm from OCT and ultrasonic corneal pachymeter respectively, there was statistical significance by paired t-test. It was divided into 4 groups by corneal thickness standardized on ultrasonic thickness measuring, paired t-test showed that when the corneal thickness≤500μm, 500μm 〈corneal thickness≤550μm, 550μm〈corneal thickness≤600μm, there were all statistical significances between ultrasonic corneal pachymeter and OCT, when the corneal thickness〉600μm, no comparison was done for little cases.
CONCLUSION: Traditional ultrasonic corneal pachymeter and OCT showe some differences and better clinical conformance on measuring corneal thickness and can be used as reference before excimer laser surgery.
出处
《国际眼科杂志》
CAS
2011年第1期117-118,共2页
International Eye Science
关键词
OCT
超声波角膜测厚仪
角膜厚度
optical coherence tomography
ultrasonic corneal pachymeter
corneal