脑脊液寡克隆区带检查对儿童病毒性脑炎的诊断价值

The Clinical Diagnostic Value of CSF Oligoclonal Bands in Children with Viral Encephalitis

为探讨脑脊液寡克隆区带检查对儿童病毒性脑炎的诊断价值，采用丙烯胺凝胶电泳法对４２例病毒性脑炎患儿脑脊液寡克隆区带进行了观测。以电泳谱上γ球蛋白的区带数及均匀程度作阳性、阴性判定。结果４２例患儿脑脊液中３２例阳性，阳性率７６．１９％；１０例阴性，阴性率２３．８１％。提示：脑脊液寡克隆区带检查在儿童病毒性脑炎的诊断中有参考价值。

In order to study the clinical diagnostic value of CSF oligoclonal bands in children with viral encephalitis, CSF of 42 children with viral encephalitis were analyzed by polyacrylamide gel electrophoresis and oligoclonal bands were observed. The standard of criticism was the number of globulin oligoclonal bands. 32 out of 42 samples were positive (76.19% positivity), the rest were negative (23.81% negativity). The result showed that CSF oligoclonal bands were of clinical diagnostic value in children with viral encephalitis.