浙江台州市椒江区726例药品不良反应报告分析

Analysis of 726 ADR Cases Reported in Taizhou City Jiaojiang District of Zhejiang Province

目的:了解浙江台州市椒江区药品不良反应(ADR)发生的特点。方法:收集到2009年浙江台州市椒江区药品生产企业、药品经营企业以及医疗机构上报的726例ADR报告,并进行回顾性归类统计和分析评价。结果:>60岁人群ADR发生率最高(占17.08%);引起ADR的主要途径为静脉滴注给药(占77.55%);最易引起ADR的药物为抗感染药(占64.74%);ADR损害类型主要以皮肤及其附件损害为主(占52.75%)。结论:临床应加强ADR的报告和监测工作,从而有利于合理用药和提高临床用药水平。

OBJECTIVE： To probe into the characteristics of adverse drug reactions （ADR） reported in Jiaojiang District. METHODS： 726 ADR cases reported by pharmaceutical enterprises, pharmaceutical trading enterprises and medical institutions were analyzed statistically and classified retrospectively. RESULTS： Of the 726 cases, 17.08% occurred in the aged people（ 〉60 years old）; 77.55% were induced by intravenous administration; 64.74% were induced by anti-infective drugs; main ADR manifestations were lesions of skin and its appendants （52.75 % ）. CONCLUSION： Great importance should be attached to ADR reporting and monitoring in the clinic so as to improve rational use of drugs.