高尿酸血症用药规律的计量学研究

Metrological Study on Prescription Pattern in Treating Hyperuricecemia

目的:对近10年高尿酸血症中医药临床治疗性文献进行用药规律的分析。方法:以中医处方用药频次进行统计分析。结果:纳入78篇文献中,用于治疗高尿酸血症的中药共计136味,依据《中药学》中各论的分类原则,利水渗湿药为14种,出现频率22.4%;清热药20种,出现频率17.1%;活血化瘀药15种,出现频率13.6%;祛风湿药18种,出现频率10.7%;补气药9种,出现频率8.1%;其余为止血药、补阳药、补血药、补阴药、解表药、消食药、温里药、化湿药、平肝熄风药、泻下药等分类。结论:初步筛选出20种使用次数显著高于其他药物的中草药,并且从用药中可以初步判断出高尿酸血症患者中医证型以湿热痹阻、痰湿阻滞、日久痰瘀阻络、阳气亏虚最为多见。

Objective： To analyze medication characteristic about hyperuricacidemia of clinical remedial literature in ten years. Method： To statistical analyzed Chinese crude drug to treat hyperuricacidemia medication frequency. Result： In 78 chapters literature, there are 136 Chinese crude drug to treat hyperuricacidemia, according to principle of classification in science of Chinese materia medica removing dampness and promoting diuresis are 14 species, frequency of occurrence is 22.4% ; heat-clearing drugs are 20 species, frequency of occurrence is 17.1% ; drug for invigorating blood circulation and eliminating stasis are 15 species, frequency of occurrence is 13.6% ; antirheumatic are 18 species, frequency of occurrence is 10. 7% ; invigorate vital energy drugs are 9 species, frequency of occurrence is 8.1% ; the are hemostyptic, reinforce yang drug, antianemic, reinforce yin drug, drugs for relieving exterior syndrome, promoting digestion drugs, drugs for dispelling internal cold, dissipating dampness drugs, drugs for calming liver to stop endogenous wind, eliminate, and so on. Conclusion： To preliminary screening 20 Chinese herbal medicines predominance more than others medicines, the major traditional Chinese medicine type of syndrome are humid heat blockage arteries and veins, phlegm stagnation, chronic stagnant phlegm and haemostasis blockage arteries and veins,yang qi weak in hyperuricacidemia patients