药物引起急性肾损伤64例临床分析

Clinical Study of 64 Cases on Drug-Induced Acute Renal Injury

目的:对64例药物引起的急性肾损伤患者进行回顾性分析,为临床合理用药提供参考。方法:对64例患者的用药种类、用药特点、肾损害临床特点及其治疗转归进行分析。结果:经停用肾损害药物,给予护肾、抗氧化、营养支持、激素、透析等治疗后,患者临床症状消失,尿常规及肾功能恢复正常。结论:药物引起的急性肾损伤,虽经积极治疗可以治愈,但我们应严格掌握用药指征,对其加以监测,避免药物性急性肾损伤的发生。

Objective： To analyze 64 cases of Drug - induced acute renal injury. So as to provide guidance for clinical rational use of these medicines. Method： The pharmacy kinds, clinical characteristic of renal damage and prognosis of 64 cases of acute renal injury were analyzed. Result：After the stopped medicament, treated with protecting kidney drugs, antioxygen, corticosterone and dialysis, clinical symptoms disappeared in all eases, their urine routine and renal function could recover. Conclusion： Drug - induced acute renal injury can cure after treating actively. But the most important is that we should handing the medication indicate strictly, and the use of medication should be monitored from different levels so as to avoid the Druginduced acute renal injury.